Advancing the science to improve the odds

MIVI is on a mission to deliver groundbreaking solutions for improving outcomes in challenging neurointerventional procedures. We go beyond current options to solve two major unmet needs identified by neurointerventionalists—improving aspiration outcomes for strokes, and reducing distal embolization.

Improving aspiration in distal strokes

Distal occlusions are notoriously difficult to access and treat. MIVI’s mission is to change that equation, by delivering uncompromising performance in even the smallest sizes.

up to40%

of all ischemic strokes are due to distal occlusions¹

~60%

of distal occlusions do not achieve TICI-2b/3 revascularization with medical management²

¹ Stroke. 2020 Oct;51(10):e296. PMID: 32757757
² Stroke. 2020 Nov;51(11):3232-3240. doi: 10.1161/STROKEAHA.120.030227. Epub 2020 Oct 19. PMID: 33070714

REDUCING DISTAL EMBOLIZATION

The risk of a clot breaking and traveling downstream is ever present. MIVI is focused on developing technologies to reduce this risk and improve patients’ outcomes.

Embolization during Mechanical Thrombectomy

Overall, 42% (21/50) of patients showed embolic events following mechanical thrombectomy, including 20% (10/50) with embolization to a distal territory (EDT), 20% (10/50) with embolization to a new territory (ENT), and 2% (1/50) with both.¹

Distal occlusions at procedure end can cause incomplete final reperfusion (Thrombolysis in Cerebral Infarction [TICI] 2a–2c rather than TICI3), larger infarcts, and worse clinical outcome.” ²

¹ Stroke. 2021 Jul;52(7):2241-2249. doi: 10.1161/STROKEAHA.120.033377. Epub 2021 May 20. PMID: 34011171
² Stroke. 2020;51:2872–2884. doi: 10.1161/STROKEAHA.120.028956

Purple = passion

Purple is our color for a reason. It stands for passion, and that’s not too strong a word for the singular focus that drives MIVI to develop unique solutions for the treatment and prevention of strokes. From the start, we have worked closely with physicians to identify pressing unmet needs and develop superior tools for challenging neurointerventional procedures.